| Brain | Acutely: Blood stasis, Cerebral edema, Elevated CSF pressure, Hemorrhages |
| . | Chronically: Diffuse cell death in many parts of brain; necrotic lesions in basal ganglia, hippocampus, cerebellum (areas of water-shed drainages); peripheral demyelination |
| Heart | Acutely: Myocardial injury and necrosis |
| . | Chronically: Myocardial infarcts |
| Lungs | Primary: Pulmonary edema, congestion |
| . | Secondary: Aspiration pneumonia in comatose patients |
| Eye | Retinal hemorrhages |
| Ear | Death of cells in the inner ear and cochlea |
| Liver & G.I. Tract | Lobar hepatic necrosis with chronic repeated exposure (rare) |
| Kidney | Acutely: failure due to myoglobinuria, usually self-corrective |
| . | Chronically: parenchymatous degeneration leading to necrosis (rare) |
| Skeletal Muscle | Intramuscular hemorrhages, swelling, rhabdomyolysis, compartment syndrome |
| Bone | Marrow hypertrophy in chronic CO-hypoxia, leading to polycythemia |
| Skin | Erythema, blisters, and gangrene (latter is rare) |
Note: The above mainly applies to higher level, acute CO exposure.
for Graphic on CO-induced Organ Damage